XQTL is a family-based allelic/haplotype association test for quantitative traits using X-linked SNP/two-locus markers in a nuclear family design. XQTL adopts the framework of the orthogonal model implemented in the QTDT program with modification of the sex-specific score for X-linked genotypes. XQTL also takes into account the dosage effect due to female X chromosome inactivation.
Zhang L, Martin ER, Morris RW, Li YJ. (2009) Association test for X-linked QTL in family-base d designs. American Journal of Human Genetics (in press).
XQTL, version 1.0, is compiled for the Windows, Solaris and Linux platforms. Please fill out the form below to download.
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