Protein Biomarkers in Precision Medicine Colloquium

8:00 am - 3:30 pm
November 22, 2019
Trent Semans Center – Great Hall
8 Searle Center Drive Durham, NC 27710
Event Contact: Erin Rhodes
Office: (919) 684-1808

Join fellow Duke researchers on Friday, November 22 for a day-long event of speakers, panels, and posters covering protein biomarkers in precision medicine!

The use of protein biomarkers in precision medicine is entering an exciting new phase with the alignment of efforts to pair clinical cohorts with detailed phenotypic information, significant improvements in sensitivity of protein assays, and the development of new approaches towards multi-dimensional data analysis. This sea-change means that we may be able to map disease development and assess protein biomarkers in larger scale epidemiologic samples to provide clues to underlying mechanisms of processes such as aging, resilience, and age-related diseases.

At Duke, there are a number of laboratories and core resources involved in various aspects of biomarker development and use. However, the advent of new technologies and their broader application demands a more coordinated approach in order to ensure the efficient and cost-effective use of patient and core resources. Towards this end, we are hosting a day-long colloquia that will be broadly accessible to Duke basic and clinical investigators to discuss study design, platforms, and applications in the field of protein biomarkers for precision medicine.

When registering below, please indicate whether or not you would like to participate in the poster session with the opportunity to win prizes! Lunch will be provided.

Hosted by

Simon Gregory PhD, Professor of Neurology; Director of Molecular Genomics Core; Director of Genomics & Epigenetics, Duke Molecular Physiology Institute

Andrew Nixon PhD, Associate Professor of Medicine, DCI; Director, Phase I Biomarker Laboratory

William E. Kraus MD, Professor of Medicine, Division of Cardiology; Co-Director of Clinical Translation, Duke Molecular Physiology Institute

Harvey J Cohen MD, Professor of Medicine, Geriatrics; Emeritus Director, Center for the Study of Aging & Human Development

AGENDA

Time Speaker(s) Session Title
8:20 am Simon Gregory PhD
Professor of Neurology
Director of Genomics & Epigenetics, Duke Molecular Physiology Institute
Welcome and Introductions
Collections
8:30 am Allan D. Kirk, MD, PhD, FACS
David C. Sabiston, Jr. Distinguished Professor and Chairman, Department of Surgery
Vice Dean for Surgical Disciplines
Duke University School of Medicine Surgeon-in-Chief
Duke University Health System
Curating Reality
9:00 am Shannon J. McCall, M.D.
Associate Professor and Vice Chair for Translational Research, Department of Pathology
Director, BioRepository & Precision Pathology Center
Protein Biomarkers in Precision Oncologic Pathology
9:30 am Russell P. Tracy, PhD, FAHA
University Distinguished Professor of Pathology & Laboratory Medicine, and Biochemistry
Director, Laboratory for Clinical Biochemistry Research
Larner College of Medicine, University of Vermont
Biorepositories in Cardiovascular Research: Special Emphasis on Cryopreserved Cells
10:10 am   Coffee Break
Discovery
10:25 am Andrew Nixon PhD
Associate Professor in Medicine, DCI
Director, Phase I Biomarker Laboratory
Implementation of Biomarkers into Clinical Trial Design
10:55 am M. Arthur Moseley PhD
Associate Research Professor
Duke Proteomics Core Facility
Mass Spectrometry-based Biomarker Discovery, Validation and Implementation for Precision Medicine
11:25 am Svati Shah MD
Professor of Medicine, Division of Cardiology
Associate Dean of Genomics
Director, Precision Genomics Collaboratory
Co-Director of Clinical Translation, Duke Molecular Physiology Institute
DNA Aptamer Based High Throughput Proteomics for Discovery of Heart Failure Biomarkers
11:55 am Gordon Broderick PhD
Director, Center for Clinical Systems Biology
Rochester General Hospital
A Whisper to a Shout: Pathological Conversations in Immune Signaling
12:35 pm   Lunch and Poster Session
Development/Application
1:15 pm L. Kristin Newby MD
Professor of Medicine, Division of Cardiology
Director, Translational Population Health Research (TransPop)
Troponin as a Prototype Biomarker for Precision Medicine
1:45 pm Virginia Byers Kraus MD, PhD, Professor of Medicine, Division of Rheumatology & Immunology and; Pathology; Orthopaedic Surgery FDA Qualification of Biomarkers
2:15 pm David Murdoch MD
Associate Professor of Medicine
Division of Pulmonary, Allergy and Critical Care Medicine
Getting a Handle on HAND: Biomarkers of Neuroinflammation and Neuronal Injury in HIV
Panel and Conclusion
2:45 pm Drs. Tracy, Broderick, Ferguson, Nixon, VB Kraus, and Shah Current topics in Protein Biomarker Discovery
3:25 pm William E. Kraus, MD
Professor of Medicine, Division of Cardiology
Co-Director of Clinical Translation, Duke Molecular Physiology Institute
Wrap up, Poster award and Adjourn
Please register below.
Note: prizes will be awarded for poster entries.