
People of African ancestry are 4 times more likely to develop kidney disease than Caucasians.
People of African ancestry have a high risk of kidney disease because of changes in the apolipoprotein L1 (APOL1) gene. |
However, not all carriers of APOL1 gene changes will develop kidney disease. |
In the US, 13% of Blacks carry APOL1 gene changes that cause kidney disease. 70% of Blacks with diagnosis of focal segmental glomerulosclerosis (FSGS) carry these APOL1 gene changes. |
Right now, there is no treatment for APOL1-associated kidney disease, and doctors don't have a way to screen for people with APOL1 gene changes who are likely to develop kidney disease. |
HELP US LEARN HOW APOL1 CAUSES KIDNEY DISEASE AND HOW WE CAN TREAT AND SCREEN PEOPLE.
YOU CAN PARTICIPATE IN THE APOL1 STUDY IF YOU:
- Are black
- Are 50 years or older
- Do not have kidney disease, diabetes, or HIV
OR
- Are black
- Have FSGS diaagnosed by a biopsy
- Do not have HIV
IF YOU DECIDE TO PARTICIPATE YOU WILL:
- Give one blood sample and one urine sample
- Answer questions about your health
This visit should take about 1 hour. You will be given a gift card to thank you for your time.

Our goal is to discover innovative prevention and cure of APOL1-Associated Kidney Disease.