JAK inhibitor blocks COVID-19-cytokine-induced JAK-STAT-APOL1 signaling in glomerular cells and podocytopathy in human kidney organoids.
Significant phenotypic associations with COVID 19 risk alleles in UK Biobank
Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis
Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart
- JAK inhibitor blocks COVID-19-cytokine-induced JAK-STAT-APOL1 signaling in glomerular cells and podocytopathy in human kidney organoids.
- Significant phenotypic associations with COVID 19 risk alleles in UK Biobank
- Steroid-sensitive nephrotic syndrome candidate gene CLVS1 regulates podocyte oxidative stress and endocytosis
- Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart
DUKE MOLECULAR PHYSIOLOGY INSTITUTE
Our mission is to produce integrated multi-omics and physiologic profiles of chronic human diseases, and to use such profiles to develop new disease detection strategies, novel therapies, and insights into disease mechanisms.
An integrative approach for innovative discoveries
DMPI RESEARCH SECTIONS
DMPI NEWS
UPCOMING EVENTS
August 22
PTEN hamartoma tumor syndrome: A personalized healthcare journey
Virtual
12:00 pm to
1:00 pm