Dr. Gupta is a Professor in the Department of Medicine and Division of Endocrinology and Metabolism. He joined the DMPI in July of 2022, after spending ten years as a faculty member in the Department of Internal Medicine and Touchstone Diabetes Center at UT Southwestern Medical Center. Dr. Gupta is the Section Chair of Basic Sciences at the DMPI. Since 2012, Dr. Gupta’s laboratory has remained laser-focused on understanding the mechanisms governing mammalian cell differentiation and tissue remodeling under physiological and pathophysiological conditions. The lab’s specific focus is on 1) the mechanisms governing the establishment and maintenance of the adipocyte lineage, and 2) the identity of adipocyte precursors and their importance to healthy adipose tissue expansion in obesity. The long-term goals are to understand how adipose tissue expands in obesity and uncover how maladaptive adipose remodeling can lead to diabetes and other chronic metabolic diseases.