Kathleen Cooney MD
Principal Investigator
George Barth Geller Distinguished Professor of Medicine
Professor of Medicine
Chair, Department of Medicine
Member of Duke Molecular Physiology Institute
Member of the Duke Cancer Institute

SUMMARY

Dr. Cooney is Chair of the Duke Department of Medicine. 

She is a medical oncologist focused in caring for men with prostate cancer, and is internationally known for her investigations focused on the genetic epidemiology of prostate cancer.

Her research led to the important discovery of a recurrent mutation in the HOXB13 gene that increases the chances of being diagnosed with prostate cancer and is estimated to account for 5 percent of hereditary prostate cancer cases worldwide. Since men with HOXB13 mutations are at an increased risk of prostate cancer, they may benefit from participation in screening and potentially prevention protocols in the future.

Dr. Cooney’s research continues with a focus on identifying germline mutations associated with lethal and aggressive prostate cancer as well as prostate cancer in African American men

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