Paul
Brian
Rosenberg
Positions
- Professor of Medicine
- Associate Professor of Pathology
- Member of Duke Molecular Physiology Institute
Paul Rosenberg MD is an Associate Professor of Medicine in the Department of Cardiology. His research program seeks to understand how changes in calcium are decoded by a cell in order to activate signaling pathways that control gene expression, proliferation, and metabolism. In particular we are interested in Ca2+ entry pathways including store-operated Ca2+ entry (SOCE) and transient receptor potential channels (TRPC). We have demonstrated that stromal interaction molecule 1 (STIM1) activates SOCE in muscle in order to adapt muscle function for exercise. In addition, we are interested in the role of TRPC channels in cardiac myocyte, islet, and podocyte cell proliferation.
Dr. Rosenberg splits his time between the lab and his work as a Transplant Cardiologist.