Demonstration of how the dual incretin agonist tirzpetide requires the GIPR in human islets for insulin secretion
Genetic epidemiology studies of chronic kidney diseases (CKD) in West Africa showed a single risk allele of the APOL1 gene is clearly associated with CKD, while the high-risk APOL1 genotype has a prevalence of up to 50% in some African populations.
Ketone flux through BDH1 supports metabolic remodeling of skeletal and cardiac muscles in response to intermittent time-restricted feeding
APOL1 G1 and G2 variants cause kidney disease by increasing Na+/K+ transport across the plasma membrane of podocytes
- Demonstration of how the dual incretin agonist tirzpetide requires the GIPR in human islets for insulin secretion
- Genetic epidemiology studies of chronic kidney diseases (CKD) in West Africa showed a single risk allele of the APOL1 gene is clearly associated with CKD, while the high-risk APOL1 genotype has a prevalence of up to 50% in some African populations.
- Ketone flux through BDH1 supports metabolic remodeling of skeletal and cardiac muscles in response to intermittent time-restricted feeding
- APOL1 G1 and G2 variants cause kidney disease by increasing Na+/K+ transport across the plasma membrane of podocytes
DUKE MOLECULAR PHYSIOLOGY INSTITUTE
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