Genetic determination of cortex structure
The human cerebral cortex is important for cognition, and it is of interest to see how genetic variants affect its structure. DMPI faculty members Allison Ashley-Koch and Mike Hauser and DMPI staff member Melanie Garrett were part of a team of researchers who combined genetic data with brain magnetic resonance imaging from more than 50,000 people to generate a genome-wide analysis of how human genetic variation influences human cortical surface area and thickness.
David D’Alessio heads Duke effort for DERC grant
We are pleased to announce the award of a new NIH Diabetes Endocrinology Research Center (DERC) grant, representing a collaboration between the Wake Forest, UNC-Chapel Hill and Duke Medical Centers.
David Bartlett Selected to Receive 2020 ASH Scholar Award
Assistant professor of Medicine David Bartlett, PhD has been selected to receive a $150,000 clinical-junior-faculty-level 2020 ASH Scholar Award by the American Society of Hematology (ASH) to study the underlying mechanisms and clinical usefulness of exercise training on the immune system of older patients with chronic lymphocytic leukemia (CLL).
Mitochondrial fuel choice impacts glucose control
A team of researchers at DMPI led by Postdoctoral Associate, Ashley Williams, and Professor of Medicine, Deb Muoio, sought to understand why mitochondria–the primary metabolic engines in most cells–begin to fail when organisms are exposed to chronic overnutrition and obesity.
Olga Ilkayeva and Chris Newgard among Most Highly Cited Researchers
The list of Highly Cited Researchers for 2019 includes two DMPI scientists: DMPI Metabolomics Core Laboratory Director Olga Ilkayeva and DMPI Director Chris Newgard. They are two of Duke’s 54 prominent and influential researchers included in the list.
Role of the gut in sepsis
A recent study by Amro Ilaiway, MD, a Duke endocrinology fellow working with DMPI Associate Director David D'Alessio, found that bacterial translocation from the gastrointestinal (GI) tract may contribute to the multi-organ failure associated with sepsis.
Rasheed Gbadegesin gives Michelle P Winn, MD Endowed Lectureship talk at ASN
Rasheed Gbadegesin, MD, MBBS, gave The Michelle P. Winn, MD, Endowed Lectureship presentation at the annual American Society of Nephrology meeting in November, 2019.
Humans Have Salamander-Like Ability to Regrow Cartilage in Joints
Exciting research from the Virginia Kraus lab, has identified a mechanism for innate cartilage repair in humans similar to that used by salamanders and zebrafish to regenerate limbs.
Chris Newgard 2020 Laureate Award Winner
The Endocrine Society, a global community dedicated to advancing hormone research, has chosen 13 leading endocrinologists as winners of its prestigious 2020 Laureate Awards, the top honors in the field.
Minimal calorie restriction shows great gains
CALERIE was a study designed to determine the biological effects of two years of prolonged caloric restriction in humans. In a paper recently published in Lancet Diabetes & Endocrinology by William Kraus and colleagues, the authors found that metabolic health was greatly improved over the course of the study.